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L-Ergothioneine is a natural molecule isolated from the ergot fungus of rye. Later, it was discovered in the red blood cells, liver, and many other animal tissues of rats.
L-Ergothioneine is transported into mitochondria through the transporter protein OCTN1 on the cell membrane and mitochondrial membrane, exerting antioxidant functions, inhibiting DNA damage, effectively protecting against ultraviolet damage, protecting cells, and preventing photoaging.
It is also a highly protective natural antioxidant for cells, non-toxic, and not easily oxidized in water, and it stimulates the body's natural antioxidant defense system. Among various antioxidants, L-Ergothioneine is particularly unique because it can chelate heavy metal ions, protecting red blood cells in the body from free radical damage.
1. Antioxidant effect: It can eliminate excessive free radicals and reduce DNA oxidative damage in skin cells. L-Ergothioneine is specifically enriched in key organs such as the brain and liver through the OCTN1 transporter, enhancing its antioxidant effect.
2. Anti-inflammatory effect: It can inhibit the oxidation of amino acids mediated by peroxynitrite anions, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.
3. Protective effect on cells: It protects red blood cells from harm caused by neutrophils originating from normal functions or pathological inflammatory sites.
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